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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPB41L4B All Species: 13.33
Human Site: S254 Identified Species: 24.44
UniProt: Q9H329 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H329 NP_060894.2 900 99712 S254 W K E C R G K S P A Q A E L S
Chimpanzee Pan troglodytes XP_520178 925 103214 S279 W K E C R G K S P A Q A E L S
Rhesus Macaque Macaca mulatta XP_001102639 820 92159 Y207 R G R D G C E Y S L G L T P T
Dog Lupus familis XP_532028 914 101864 S294 W K E C R G K S P A Q A E L S
Cat Felis silvestris
Mouse Mus musculus Q9JMC8 527 59559
Rat Rattus norvegicus B2RYE5 527 59553
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509941 820 90648 F207 P K I T R L D F K K N K L T L
Chicken Gallus gallus XP_419046 839 94372 L219 Y L N K A K W L E M Y G V D M
Frog Xenopus laevis NP_001080234 498 57093
Zebra Danio Brachydanio rerio O57457 619 70690
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650291 972 105216 T227 Y K T C R G L T P A Q A E T A
Honey Bee Apis mellifera XP_623974 809 90976 R196 I G P P Y T L R L K V K F Y S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788387 843 92835 L222 Y L N K A K W L E M Y G V D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88 89.1 84.5 N.A. 54.6 54.6 N.A. 35.2 67.1 36.4 25.4 N.A. 33.9 35.3 N.A. 34.6
Protein Similarity: 100 89.8 90 86.9 N.A. 56.6 56.8 N.A. 47.7 75.3 45.4 40.7 N.A. 49.2 52 N.A. 50.1
P-Site Identity: 100 100 0 100 N.A. 0 0 N.A. 13.3 0 0 0 N.A. 60 6.6 N.A. 0
P-Site Similarity: 100 100 13.3 100 N.A. 0 0 N.A. 13.3 6.6 0 0 N.A. 80 6.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 16 0 0 0 0 31 0 31 0 0 8 % A
% Cys: 0 0 0 31 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 8 0 0 0 0 0 0 16 0 % D
% Glu: 0 0 24 0 0 0 8 0 16 0 0 0 31 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % F
% Gly: 0 16 0 0 8 31 0 0 0 0 8 16 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 39 0 16 0 16 24 0 8 16 0 16 0 0 0 % K
% Leu: 0 16 0 0 0 8 16 16 8 8 0 8 8 24 16 % L
% Met: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 8 % M
% Asn: 0 0 16 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 8 0 8 8 0 0 0 0 31 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 31 0 0 0 0 % Q
% Arg: 8 0 8 0 39 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 24 8 0 0 0 0 0 31 % S
% Thr: 0 0 8 8 0 8 0 8 0 0 0 0 8 16 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 8 0 16 0 0 % V
% Trp: 24 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % W
% Tyr: 24 0 0 0 8 0 0 8 0 0 16 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _